In recent years, following the groundbreaking achievements of chimeric antigen receptor (CAR) T cell therapy in hematological cancers, and advancements in cell engineering technologies, the exploration of other immune cells has garnered significant attention. CAR-Therapy extended beyond T cells to include CAR natural killer (NK) cells and CAR-macrophages, which are firmly established in the clinical trial landscape. Less conventional immune cells are also making their way into the scene, such as CAR mucosal-associated invariant T (MAIT) cells. This progress is advancing precision medicine and facilitating the development of ready-to-use biological treatments. However, in view of the unique features of natural killer cells, adoptive NK cell immunotherapy has emerged as a universal, allogenic, “off-the shelf” therapeutic strategy. CAR-NK cytotoxic cells present targeted tumor specificity but seem to be devoid of the side effects associated with CAR-T cells. CAR-NK cells appear to be potentially promising candidates for cancer immunotherapy. However, their application is hindered by significant challenges, particularly the limited persistence of CAR-NK cells in the body, which poses a hurdle to their sustained effectiveness in treating cancer. Based upon the foregoing, this review discusses the current status and applications of both CAR-T cells and CAR-NK cells in hematological cancers, and provides a comparative analysis of the structure, genetics, and clinical outcomes between these two types of genetically modified immune cells.
This paper, prepared by Kevork Koukounian, Thalia Haboyan, and Narine Haroutounian highlights the anatomy, physiology, and biochemistry of muscles during exercise, which aim to support the healthy function of the human body.
This document by student Marc Haydamous, explores the potential impact of human cloning on biodiversity. It considers whether clones can promote genetic advancement without negatively impacting biodiversity and highlights the need for careful consideration of the potential risks and benefits of cloning, the ethical implications of creating clones, and the impact of cloning on the environment. The document also discusses the history of animal cloning and the current state of human cloning technology, as well as the potential long-term repercussions of cloning on evolution. Ultimately, the author argues that cloning has changed society's perception of the value of human uniqueness and that the cloning debate is far from being decoded.
With the ever-increasing population, it is essential to create a genetically compassionate world. In their academic paper, students <strong>Nour Hmaidi</strong>, <strong>Pamela Laylo</strong>, <strong>Muhieddine Beydoun</strong>, <strong>Tarek Fakih</strong>, and <strong>Khalil Bilani </strong>provide an in-depth look into how we can achieve that. They seek to prove that natural selection plays a pivotal role in preserving a society's survival and adaptable traits, namely ruthless or compassionate behavior, and although behavior is genetic, ruthlessness can be reversed through empathy, cooperation, and sacrifice.
With the increasing rate of death caused by Cancer, it is essential to introduce new treatment method to help patients in their fight against this deadly disease. In this paper, students Tarek Fakih, Karim Assi, and Muhieddine Beydoun provide an overview of the most effective methods for cancer treatment with the focus on treatments based on Fluid Mechanics.
This paper, prepared by Gabriel Tabbal, explores the concept of dualism in anthropology, focusing on the relationship between the mind and body as unique components of the human person. It discusses how different cultures have approached the mind-body problem, highlighting the nuanced perspectives on the age-old question. The paper also discusses the evolution of dualism, particularly through the work of French philosopher René Descartes and the rise of neuroscience in the 20th century.
This presentation underscores the complex neurological and chemical processes underlying human attraction and love. The researchers, drawing from scientific studies, emphasize how hormones, such as dopamine, oxytocin, and Vasopressin, brain regions like the reward system, and individual experiences influence our feelings and behaviors in fostering healthy romantic relationships.
This short movie is a thought-provoking material that delves into the unsettling reality of both smoking and football playing as coping strategies among children in Gaza. The piece transcends traditional storytelling to capture the real-life scenes of smoking and playing, as genuine moments that provide a stark glimpse into the daily lives of these young souls. The authentic scenes, designed and produced by the authors, seamlessly weave together the contrast of children finding solace in smoking, a coping mechanism born out of the exceptionally challenging circumstances, and the genuine, fleeting happiness derived from moments of play. The movie serves not only sheds light on the resilience of Gaza's children but also prompts reflection on the importance of fostering a future where children’s dreams can thrive. The film serves as a poignant reminder that, even in the face of uncertainty, the indomitable spirit of children can illuminate a path towards a brighter and more hopeful tomorrow.
The oral narratives of war share a number of essential characteristics. They usually have an introduction, rising action, climax, falling action, and resolution, and they frequently have a distinct beginning, middle, and conclusion. Through a semi-structured, uncensored interview with an old Lebanese woman from the North of Lebanon, the short movie pictures the ways in which personal stories are generated as means of survival, coping mechanisms and gestures of commemoration that are brought together to unfold the relationships between the collective memory and individual versions of war stories.
The short movie portrays the profound impact of violence on mental health. Through compelling facts, numbers, and visual representation, the designed script reveals the emotional and psychological toll that exposure to violence takes on those enduring the silent battles within their minds. It communicates the importance of acknowledging and addressing the mental health consequences of violence, and can serve as a powerful advocacy tool, fostering awareness about the need for support systems, empathy, and accessible mental health resources for individuals affected by violence.
Through picturing the cinematic journey of two young Lebanese students, this compelling short movie portrays the multifaceted impact of the Beirut port explosion on young people in August 2020. The film delicately strikes a balance between scenes of adversity and scenes of growth, demonstrating the resilience and determination of the youth in the face of immense challenges. It delicately unveils how the younger generation, faced with the aftermath of the tragedy, became catalysts for positive change, highlighting how they channeled their energy into rebuilding and fostering a sense of hope. The script delves into the emotional and psychological impact on young individuals, illustrating how they turned their grief into a force for resilience. The movie not only sheds light on the challenges faced by the youth but also celebrates their adaptability and determination to shape a better future.
The short film captures the everyday life of a young woman grappling with an innate disability. In response to her request, the authors of the project have meticulously depicted every facet of adversity-activated development in her journey. While the scenes unfold as a poignant portrayal of the young female’s daily routine, emphasizing the unique challenges she faces due to her disability with unwavering resolve, they also skillfully highlight moments of resilience, determination, and personal triumph. The storytelling goes beyond the surface, delving into the emotional and psychological aspects of her experience.
Mental illnesses and suicide have been main focal points of interest amongst the medical community, and especially psychologists and therapists, due to their distinctive anti-life nature. Though not a recent topic of controversy, medical assistance in dying, specifically MAiD-NT (medical assistance in dying for non-terminal diseases), has reinvoked the hot debate. The objective of this study is to illuminate the current legal state of medical assistance in dying and investigate its ethical ramifications, particularly regarding mental illnesses. We have employed a mixed-methods approach comprising surveys, interviews, and analysis of secondary data to obtain insights into both public and professional opinions. Though we found that the idea of medical assistance in dying is still a highly controversial one, the findings underscore the complex ethical and legal challenges that arise when considering MAiD for individuals with mental illnesses, particularly in determining the eligibility criteria for this practice and whether mental health conditions can justifiably be deemed incurable. The study also highlights the ongoing tensions and the critical need for continued dialogue in navigating these sensitive issues.
This manuscript investigates the efficacy of laughter therapy and positive thinking as complementary treatments for individuals with chronic diseases in Lebanon, amidst an ongoing economic crisis. Traditional biomedical treatments, while essential, are becoming increasingly costly, highlighting the need for cost-effective, alternative therapeutic approaches. This study explores the mental, physical, and economic impacts of laughter therapy and positive thinking. Findings suggest these therapies can enhance psychological well-being, manage symptoms, and potentially reduce healthcare costs, offering a holistic approach to chronic disease management.
The speech examines the psychological effect of social media during times of crisis. Consuming war-related social media content can lead to exaggeration, misinterpretation, emotional and psychological overwhelm, and disconnection. To protect our wellbeing, actionable steps should be taken to mitigate the negative influence of social media, such as verifying sources, limiting exposure, following reputable accounts, using fact-checking tools, and engaging in positive online communities.
This speech explores the nature vs. nurture debate by examining the complex relationship between parental mental health and child development. It investigates how both genetics and environment play a key role in shaping the mental health of the child either positively or negatively.
This speech discloses the secrets that make a "Super Star Student”. There is no magic formula but a combination of personal skills and healthful habits. The writers, Clara Najjar and Rhea Hnein, students themselves, address the challenges most of their classmates face, including time management, resilience, and well-being maintenance.
For lovers of musicals, The Phantom of the Opera is a timeless classic that combines a captivating story, a memorable soundtrack and top-notch acting. Read the critique, and I guarantee it will become your new favorite!
Attention movie-lovers! Are you looking for a reliable review of the movie 'The Good Nurse'? Then, look no further! Student <strong>Mohamad Shaib</strong> has all the information you need for a unique movie experience. He explores 'The Good Nurse' in this unbiased critique, highlighting the powerful performances, pacing and cinematography.
The speech seeks to unveil the enigma behind the unexplained Bermuda Triangle disappearances of ships and planes, by highlighting three theories: Time vortex, extraterrestrial activity, and the lost city of Atlantis. However, these theories remain inconclusive, adding to the allure of this intriguing topic.
This paper, prepared by Marc Haydamous and Gabriel Tabbal, explores the topic of Non-Fungible Tokens (NFTs), specifically their impact on the art industry and the potential benefits and challenges it poses to artists. The authors provide an overview of the technology and its application, highlighting the unique features that make NFTs valuable for digital art and collectibles. They also discuss the challenges facing the market, including the lack of identity restrictions, scams, and trickeries. The authors argue that despite the challenges, NFT artworks are here to stay, and could be a valuable tool for independent artists to market their art, grow a following, and make a living out of the art they sell in token form.<br /> The authors provide insights from a live interview with a top NFT one-of-one artist, Ralph Khoury, who goes by the alias of “@Gingerpotter21” on Instagram. The interview sheds light on the impact of NFTs on artists' relationship with their art, the main benefits of NFTs for artists, the importance of establishing a local community of knowledgeable connoisseurs, and the potential for NFTs to create passive income for artists.<br /> Overall, the paper provides a comprehensive overview of the potential impact of NFTs on the art industry and highlights the opportunities and challenges it poses for artists.<br /> <div> </div>
